Journal article
Cumulative trauma load and timing of trauma prior to military deployment differentially influences inhibitory control processing across deployment
LN Miller, D Forbes, AC McFarlane, E Lawrence-Wood, JG Simmons, K Felmingham
Scientific Reports | NATURE PORTFOLIO | Published : 2023
Abstract
Military personnel experience high trauma load that can change brain circuitry leading to impaired inhibitory control and posttraumatic stress disorder (PTSD). Inhibitory control processing may be particularly vulnerable to developmental and interpersonal trauma. This study examines the differential role of cumulative pre-deployment trauma and timing of trauma on inhibitory control using the Go/NoGo paradigm in a military population. The Go/NoGo paradigm was administered to 166 predominately male army combat personnel at pre- and post-deployment. Linear mixed models analyze cumulative trauma, trauma onset, and post-deployment PTSD symptoms on NoGo-N2 and NoGo-P3 amplitude and latency across ..
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Awarded by U.S. Department of Defense
Funding Acknowledgements
We acknowledge the Brain Resource Ltd., Sydney, Australia for providing the platform and data cleaning and extraction of the EEG data for this study. Data used in preparation of this manuscript were from the MEAO Prospective Study, conducted by the Centre for Military and Veterans Health (CMVH), University of Adelaide, with the Department of Defence and the Department of Veterans' Affairs. As such, we acknowledge all the study investigators who contributed to the design and implementation of the MEAO Prospective Study and/or provided data but did not participate in analysis or writing of this manuscript. The MEAO Prospective study was funded as part of the Military Health Outcomes Program, by the Department of Defence and the Department of Veterans' Affairs. In addition, L.M received a PhD stipend funded by a National Health and Medical Research Council Program Grant (1073041) awarded to K.F and A.McF.